Neo-Antial

Neo-Antial 

(Desloratadine)

DESCRIPTION:

Also for the in ampincal formula CrHtCIN and a molecular weight of 3108. The chemical name is -chloro-811-cf has the following truc Serzo.fcydohepta(1,2-6 pyridine and has the following struchure.

Neo-Antial  COMPOSITION:

Neo-Antler Sing Tablets

Each tim coated tablet canlang Desloratadin MS 5mg

Neo-Ratial 0.5mg/md Syrup contam

Desbetadine

CLINICAL PHARMACOLOGY

Instrument of Desloratadine isa long-acting tricyclic vistamine adversary with specific H1 receptor bad guy action.

PHARMACOKINETICS:

Also for the volunteers, the maan tame to maximum plasma concentrations (Emaux) sccurred at approximately ratadine Following oral administration of destoratadine 5mg once dally for 10 days to normal healthy volu terature (AUC) of 4mg/ml and 56 Sing hriml were observed, respectively 3 hours post dose and mean steady state peak plasma concentratic atione (Gtmas) and area under Neither food nor grapefruit juice had an effect on the bioavailability (Cmax and AIC) of deslorat.

Distribution: Distellaudine and 3-hydroxydotioratadine ane accoroxanately 82% to 87% and 85% to 89%, bound to platma proteins respectively Protein binding of desloratadine und 3inydirtydesinine unaltered in subjects with impaced renal function.

Metabolism:

Desloraladine (a maior metabolite of loratadine) is extensively melatiolized to 2-hydroxydesloratadine identified for the formation of 3-hydroxydesloratadine have not been identified an active metabolts, which is subsequently glucuronidated. The enzymes responsible. Also mean almination hailife of desloratadine is 27 hour is 27 hours Cmax and AJC values increased in a dose proportional manner following single aral doses between 5 accumulation after 14 days of dosing was consistent with the the hall ids ar and and dosing frequency Sand 20mg.

Elimination:

Pharmacodynamics Human nistan:

Also for the  drug exhibits an antihistaminic effect by 1 hour this activity may persist repeated Sing deses of desloratadine have shown that the stamine skin whaal studies following single and for as long as 24 hours.

INDICATIONS AND USAGE:

Seasonal Allergic Rhinitis:

Neo-Antal indicated for the relief of the natal and non nasal symptoms of seasonal allergic rhinitis in patenta 2 years of age and older.

Perennial Aliergic Rhinitis:

Neo-Antlersindicaled for the relief of the nasal and non-nasal symptoms of perermial allergic rhinitis in patients 6 months of age and older Chronic Idiopathic Urticaria thic Urticaria.  Neo-Antial indicated for the symptomatic mlief of pruritus retuation in t the number of hives and size of hiss in patients with chronic idiopathic urticana months of age and oder.

CONTRAINDICATIONS Noo-Antial

contraindicaled in patients when arm to any of its ingredients or to loratadine hypersensitive to this medication.

PRECAUTIONS Pregnancy Category C:

Therm as no adequate and well-controlled studies in pregnant woman the drug to the mother.

Paediatric Use:

Also safety and effectiveness of Meo-Antlaf tablets or Neo-Antial syrup have not been demonstrated.

Adverse Reactions: The common adverse events are pharyngitis, dry mouth, myalgia, fatigue, samnolence and dysmenonтва.

DOSAGE AND ADMINISTRATION:

Grown-ups and kids 12 years old and over.

Children 6 to 11 years of age:

The recommended dose of Neo-Astial syrup is 1 teaspoonful (2.5mg in 5ml) once dally.

Children 12 months to 5 years of age: Also  for the recommended dose of Neo-Antial syrup is 1/2 teaspoonful (1.25mg in 2.5ml) once daily.

Children & to 11 months of age: Also recommended dose of Neo-Antlal syrup is 2ml (1.0mg) once deity.

Adult patients with Hepatic or renal impairment: Also for the  starting dose of one 5mg tablet every other day is recommended.

OR As directed by the physician

نیو انتيال ملك ایری

PRESENTATION:

Neo-Antial: 5mg tablets in blister pack of 10’s Neo-Antial syrop in pack of 60ml stabilaty see expiry on the pack.

INSTRUCTIONS:

Keep out of reach of children. Avoid exposure to heat, light, humidity and freezing Store between 15 to 30°C. Improper storage may delenorate the medicine.

Caution: Medione should not be used if container is leaking or it contains un-dissolved particiels)

Manufactured by:

(ڈیس اور اٹاڈین)

خوراک: ڈاکٹر کی ہدایت کے مطابق استعمال کریں بچوں کی پہنچ سے دور رکھیں

دوا کو دھوپ ، گرمی، ہمیں اور محمد ہونے سے محفوظ ۱۵ سے ۳۰ ڈگری سینٹی گریڈ کے درمیان میں رکھیں ورنہ دو اخراب ہو جائیگی

حیہ : دوا کے ایک ہونے ، دھندلا ہونے یا اس میں کوئی غیر حل پزیر شے نظر آنے کی صورت میں ہرگز استعمال نہ کریں۔

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