Zoltum Insta (Omeprazole Sodium Bicarbonate)
:زولتم انستا ساشے پاؤڈر برائے س
DESCRIPTION:https://luckasluck.click/Zoltum Insta (Omeprazole Sodium Bicarbonate)/
ZOLTUM INSTA: contains immediate-release formulationa of omeprazole
ZOLTUM INSTA: Sodium bicarbonate raises the gastric pH and thus protect omeprazole from acid degradation.
QUALITATIVE & QUANTITATIVE COMPOSITION:
1. ZOLTUM INSTA: Powder for Suspension 20mg Each sachet contains:
Omeprazole USP…….. .20mg Sodium Bicarbonate USP……1680mg (As per Innovator’s Specs.)
2. ZOLTUM INSTA: Powder for Suspension 40mg
Each sachet contains:
Omeprazole USP…. …40mg Sodium Bicarbonate USP……1680mg (As per Innovator’s Specs.)
ZOLTUM INSTA: (Omeprazole +Sodium Bicarbonate) powder for suspension is indicated:
1. The treatment of Gastro-Esophageal Reflux Disease (GERD):
For the treatment of heart burn and other symptoms associated with GERD.
For the treatment of erosive esophagitis which has been diagnosed by endoscopy.
2. Short term treatment of active duodenal ulcer. Some patients may require an additional therapy.
3. Short term treatment of active benign gastric ulcer
4. For maintenance treatment of healing of erosive esophagitis.
5. For reduction treatment of risk of upper gastrointestinal bleeding in critically ill patients.
DOSAGE AND ADMINISTRATION:
ZOLTUM INSTA: (Omeprazole + Sodium Bicarbonate) for oral suspension as per recommended dosing given in table below.
ZOLTUM INSTA: (Omeprazole + Sodium Bicarbonate) should be taken on an empty stomach at least one hour before a meal.
Also for the Empty the sachet contents into a small cup containing 1-2 tablespoons (11 30ml) of water to protents into a small cup containing 1-2 tamediately. Refill cup with water and drink, DO NOT USE OTHER LIQUIDS OR FOODS.
– Omeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation.
– Sodium bicarbonate is contraindicated in patients with metabolic
alkalosis and hypocalcemia.
PRECAUTIONS:
General
– Symptomatic response to therapy with omeprazole does not preclude the presence of gastric malignancy.
– Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-tenm with omeprazole.
– Omeprazole powder for oral suspension contains sodium in the form of sodium bicarbonate. This should be taken into consideration for patients on a sodium restricted diet.
– Sodium bicarbonate should be used with caution in patients with bartter’s syndrome, hypokalemia, respiratory alkalosis, and problems with acid-base balance. Long-term administration of bicarbonate with calcium or milk can cause milk-alkali syndrome.
DRUG INTERACTIONS:
There have been reports of increased INR and prothrombin time in patients receiving proton pump inhibitors, including omeprazole, and warfarin concomitantly. Increase in INR and prothrombin time may lead to abnormal bleeding and even death. There have reports of interaction with other drugs metabolized via been clinical the
Because of its profound and long-lasting inhibition of gastric acid secretion, it is theoretically possible that omeprazole may interfere with absorption of drugs where gastric pH is an important determinant of their bioavailability (e.g. Ketoconazole ampicillin esters, and iron salts).
Concomitant administration of omeprazole and tacrolimus may increase the serum levels of tacrolimus. Co-administration of omeprazole and clarithromycin have resulted in increases of plasma levels of omeprazole. Clarithromycin, and 14-hydroxy-clarithromycin.
There are no adequate and well controlled studies on the use of omeprazole in pregnant women.
Metabolic/Nutritional Hyponatremia, hypoglycemia and weight gain.
Musculoskeletal Muscle cramps, myalgia. muscle e weakness, joint pain, and le Dint maceu pain, and leg p pain.
OVERDOSE:
Also for the In doses ranged up to 2400mg, manifestations were variable, but included confusion, drowsiness, blurred vision, tachycardia, nausea, vomiting, diaphoresis, flushing, headache, dry mouth, and other adverse reactions similar to those seen in normal clinical experience. In addition, a sodium bicarbonate overdosage may cause hypocalcemia, hypokalemia, hypernatremia, and seizures.
Store between 15°C -30°C
Protect from heat, moisture and sunlight.
Keep out of the reach of children.
ZOLTUM INSTA: Also 20mg Powder for suspension is available as sachet in pack of 7’s, 10’s and 50’s.
ZOLTUM INSTA: suspension of 7’s, 10’s and 50’s. ng Powder for is available as sachet in packicals
ڈاکٹر کی ہدایت کے مطابق استعمال کریں۔
ز وائم انسٹا سپنشن بنانے کے لئے پاؤڈر کو 1 سے 2 کھانے کے چمچے (15) سے 30 ملی لیٹر پانی میں حل کریں۔ تیار شدہ سپنشن کو فوراً استعمال کرلیں۔ کپ میں دوبارہ پانی بھریں اور پی لیں۔ پانی کے علاوہ کسی اور شے کے ساتھ استعمال نہ کریں۔ ہدایات: دوا کو 15 سے 30 ڈگری سینٹی گریڈ کے درمیان رہیں۔
گرمی نمی اور دھوپ سے بچائیں۔ بچوں کی پہنچ سے دور رکھیں ۔